Patient handout
Buspirone (Buspar)
You have been prescribed buspirone. This page explains what it is, what to expect, and when to call.
What it is
Buspirone is a daily anti-anxiety medication for generalized anxiety. It is not a benzodiazepine and not an antidepressant. It does not cause sedation, dependence, or withdrawal, which is why it is often chosen. It is sometimes added to an SSRI or SNRI to strengthen the effect.
How to take it
- Take it two or three times a day as prescribed, at the same times each day.
- Take it consistently with food or consistently without, since food changes how much is absorbed.
- It is not an as-needed medication. It only works when taken every day.
- If you miss a dose, take it when you remember unless the next dose is close. Do not double up.
What to expect, and when
- Week 1 to 2: mild dizziness or nausea are the most common early effects and usually pass.
- Week 2 to 4: worry and tension often begin to ease.
- Week 4 to 6: full benefit at the right dose. It works more gradually than a benzodiazepine, by design.
- It tends to work less well in people who have taken benzodiazepines regularly in the past.
Common side effects
Dizziness, lightheadedness, nausea, headache, nervousness, and trouble sleeping. Most are mild. It does not usually cause weight gain or sexual side effects.
Call the office the same day if
- Fainting, chest pain, or a very fast heartbeat
- Severe dizziness that does not settle, or trouble with balance
- Fever with agitation, muscle twitching, or confusion, especially if you also take an antidepressant (possible serotonin syndrome)
- Rash, swelling, or trouble breathing (call 911)
- Any new or worsening thoughts of hurting yourself
Stopping
Buspirone does not cause withdrawal, so stopping is simpler than with other anxiety medications. Still, tell us before stopping so we can plan what comes next for your anxiety.
Good to know
- Avoid large amounts of grapefruit juice, which raises buspirone levels.
- Tell other prescribers and your pharmacist. Buspirone should not be combined with MAOI antidepressants, and some antibiotics and antifungals raise its level.
- Until you know how it affects you, be careful driving.
Questions about this medication?
Alice Tran Psychiatric Care · 3060 Williams Drive, Suite 300, Fairfax, VA 22031
Call: (703) 791-9099 · Text: (703) 791-9031 · info@alicetrannp.com · alicetrannp.com
This handout is for education and is not a substitute for the instructions you received at your visit. Follow the dose on your prescription label. If anything here differs from what you were told, call the office. In an emergency, call 911. If you are in crisis, call or text 988.